nude mouse

nude mouse
a mouse born without a thymus and therefore no T-lymphocytes. Human tumours will often grow in these mice. For unknown reasons these mice are also hairless, hence the name.

The new mediacal dictionary. 2014.

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  • nude mouse — n(y)üd n a mouse of a hairless strain bred for laboratory use that lacks a thymus and mature T cells and is used esp. in immunological research * * * a mouse born without a thymus and therefore no T lymphocytes. Human tumours will often grow in… …   Medical dictionary

  • nude mouse — nude′ mouse′ n. bio lab a hairless mutant laboratory bred mouse having an immune system deficiency and able to accept grafts of foreign tissue …   From formal English to slang

  • Nude mouse — A nude mouse A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. The phenotype, or main outward… …   Wikipedia

  • nude mouse — noun a mouse with a genetic defect that prevents them from growing hair and also prevents them from immunologically rejecting human cells and tissues; widely used in preclinical trials • Hypernyms: ↑mouse * * * noun : a mouse of a hairless strain …   Useful english dictionary

  • nude mouse — a virtually hairless mutant laboratory bred mouse having a major immune system deficiency caused by a lack of T cells, and able to accept grafts of foreign tissue. [1965 70] * * * …   Universalium

  • athymic nude mouse — A type of laboratory mouse that is hairless, lacks a normal thymus gland, and has a defective immune system because of a genetic mutation. Athymic nude mice are often used in cancer research because they do not reject tumor cells, from mice or… …   English dictionary of cancer terms

  • nude-мыши безволосые м — nude мыши, безволосые м. * nude мышы, безвалосыя м. * nude mouse лабораторная линия мышей, гомозиготных по рецессивной мутации nu (хромосома 11). Характеризуются полным отсутствием шерсти и тимуса. n. м. лишены Т лимфоцитов (), но имеют природные …   Генетика. Энциклопедический словарь

  • Мышь, Лишенная Волосяного Покрова (Nude Mouse) — мышь, у которой с рождения отсутствует вилочковая железа и поэтому в ее организме не вырабатываются Т лимфоциты. У таких мышей часто образуются опухоли, характерные для человека. В силу неизвестных причин у этих мышей отсутствует волосяной покров …   Медицинские термины

  • mouse — A small rodent belonging to the genus Mus. joint mice Small fibrous, cartilaginous, or bony loose bodies in the synovial cavity of a joint. knockout m. a m. from whose genome a single gene has been artificially deleted.Experimental animals… …   Medical dictionary

  • Humanized mouse — The “humanized mouse” is a mouse carrying functioning human genes, cells, tissues, and/or organs that are initially transplanted and grown in it. It has been often used as in vivo human models in the area of biological and medical research for… …   Wikipedia

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